Phenylcarbamic acid esters
Medchemexpress LLC N-desmethyl clomipramine-d3 hydrochloride | 1189971-04-7 | MFCD28899247 | 99.8% | 340.31 g/mol | C18H19D3Cl2N2 | 1MG
N-Desmethyl clomipramine-d3 hydrochloride is the deuterium-labeled hydrochloride salt of N-desmethyl clomipramine (norclomipramine), supplied for research and analytical applications. It is intended primarily as an internal standard for quantitative mass spectrometry and pharmacokinetic studies involving clomipramine metabolism.
- Deuterium-labeled internal standard for mass spectrometry.
- Suitable for pharmacokinetic and metabolic studies.
- High chemical purity, 99.8%.
- Provided as a hydrochloride salt for improved solubility.
- Available in small analytical pack sizes for research use.
Selleck Chemical LLC N-Acetylglucosamine
N-Acetylglucosamine (GlcNAc) is a monosaccharide that usually polymerizes linearly through (1 4)- -linkages It may be helpful for the treatment of autoimmune diseases
Medchemexpress LLC N-Descyclopropanecarbaldehyde Olaparib | 763111-47-3 | 98.7% | C20H19FN4O2 | 1 ML
N-Descyclopropanecarbaldehyde Olaparib is an analogue of Olaparib containing a DOTA moiety. It acts as a PARP inhibitor and is utilized in the synthesis of novel dual EGFR and PARP PROTACs. This compound can be radiolabeled with F-18 or a fluorophore for positron emission tomography (PET) or optical imaging in various tumor types.
- Acts as a PARP inhibitor
- Used for the synthesis of novel dual EGFR and PARP PROTACs
- Can be radiolabeled for PET or optical imaging in various tumor types
- Exhibits antiproliferative activity against BRCA deficient human DLD1 cells (EC50: 0.2 μM)
- Inhibits human HeLa cell derived PARP (IC50: < 20 nM)
eMolecules ChemScene / Amino-PEG10-Boc / 100mg / 632318510 / CS-0114548 / 0.000 / 1818294-42-6 / MFCD26127812 / 585.732 / C27H55NO12
ChemScene / Amino-PEG10-Boc / 100mg / 632318510 / CS-0114548 / 0.000 / 1818294-42-6 / MFCD26127812 / 585.732 / C27H55NO12
Medchemexpress LLC 4-(4-Boc-piperazinemethyl)phenylboronic acid pinacol ester | 470478-90-1 | 98.5% | C21H33BN2O4 | 100 G
4-(4-Boc-piperazinemethyl)phenylboronic acid pinacol ester is a PROTAC linker utilized in the synthesis of CST905. This compound functions as part of Proteolysis Targeting Chimeras (PROTACs), which are molecules designed to selectively degrade target proteins by harnessing the intracellular ubiquitin-proteasome system. PROTACs achieve this by using two ligands connected by a linker: one binds to an E3 ubiquitin ligase, and the other targets a specific protein. This product is for research use only.
- Functions as a PROTAC linker
- Used in the synthesis of CST905
- Exploits the intracellular ubiquitin-proteasome system
- Designed for selective degradation of target proteins
- Purity is 98.50%
- Molecular weight is 388.31
- Appearance is solid, white to light yellow
Medchemexpress LLC N-Nornuciferine | 4846-19-9 | 1 ML
N-Nornuciferine is an aporphine alkaloid derived from lotus leaf. It is known for its significant inhibitory activity against the CYP2D6 enzyme, with IC50 and Ki values of 3.76 μM and 2.34 μM, respectively.
- Derived from lotus leaf
- Selectively inhibits CYP2D6 activity
- Shows weak or no inhibition of other P450 isoenzymes (CYP2C19, CYP3A4, CYP2E1, CYP2C9)
- Competitively inhibits dextromethorphan o-demethylation